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Contrast Material: How Does It Work?

If you’ve ever had imaging, such as an MRI or CT scan, it’s more probable that your normal contrast.

MRIs (magnetic resonance imaging) and CTs (computed tomography) are types of devices used in the medical field that create a picture of the structures and organs inside your body. Contrast material produces a sharper image. Contrast material improves image quality in a few ultrasound and x-ray examinations as well. For the most part, contrast material can help the radiologist distinguish normal from abnormal processes.

Contrast agents do this by changing the imaging devices means of interaction with your body temporarily. Some contrast agents can also slow the speed of x-ray lights. Other contrast agents temporarily stuck to the magnetic properties of certain atoms of the body. 

In this case, using contrast agents can make certain structures and tissues appear differently in the images as well as help the structure and tissue be “contrasted” against the other tissues visible in the image.  Contrast agents improve brightening of blood vessels, tissues, and certain organs to assist physicians in identifying disease.

Types of Contrast

There are a wide variety of contrast materials, each of which works in a unique way.

Barium-sulfate and iodine compounds, to be used in x-ray and CT scan imaging

Contrast agents can take up elements with a chemical composition that entails iodine, a naturally occurring chemical compound. Such a type of contrast is injected into the vessels of the bloodstream, into the fluid spaces of the spine or bathed in the rubbery-like discs cushioning the bones in the spine, and into the body cavities.

Barium-sulfate preparations are the most frequently used oral contrast substances, although they can be administered rectally. Barium-sulfate preparations are present in some variety of form, including powder that is dissolved in water before administration, liquid, paste, and tablet.

X-rays and CTs work by sending x-ray beams through your body to an x-ray detector, which absorbs the x-rays to form a picture. Your body tissues and bones may also absorb the x-ray, depending on their size, to slow down the beam or stop it entirely. As a result, the x-ray beams form “shadows” that project the tissues and organs onto the pictures.

Iodine-based and barium sulfate agents block or bind to x-rays as they penetrate through tissue. There are then specific reflections to look at the blood vessels, organs, and other body tissues with the x-ray or CT scan reflecting barium sulfate or iodine based chemicals. 

Doctors usually rely on oral barium sulfate agents to enhance x-ray and CT imaging of the gastrointestinal tract, which comprises the pharynx and esophagus, stomach, small intestines, and colon (or large intestine). Doctors usually prescribe rectal barium sulfate agents to enhance x-ray and CT imaging of small intestine and colon. When clinicians prescribe intravenous contrast that contains iodine it is to assist with x-ray and CT scans of the internal organs, such as the heart and lungs, gastrointestinal tract, arteries and veins, the brain, and breast tissue and squishy body tissues, supporting muscles and fat.

Gadolinium

Gadolinium is the principal element in the most commonly used routinely utilized MRI contrast agent. MRIs use strong magnets that behave upon protons, which are constituents of a proton containing a positive electrical charge. Protons always spin, but sometimes at different speeds and directions, depending upon a mix of features of the tissue; that is, protons in a healthy segment of tissue can spin in your own direction versus the protons in diseased tissue. The magnetic field causes the protons to precess out of synchrony. When the magnetic field is deflected away, the protons re-synchronize with the magnetic field at different rates, depending on tissue type; they also emit different amounts of energy, depending on tissue class.

Gadolinium changes water molecules’ magnetic chattels to increase the rate at which protons align with the dominant field; the quicker the protons, the brighter the image.

Doctors prescribe the intravenous injection of gadolinium to improve MRI images of internal organs, gastrointestinal tract, blood vessels, brain, breast tissue, and soft tissues of the body.

Saline (salt water) and air are also superior contrast materials for utilization in imaging tests. Ultrasound imaging, specifically ultrasound imaging of the heart, can make use of microbubbles and microspheres to enhance organs and tissues to become brighter visible on ultrasound. These contrast materials are appropriate for identifying the functioning of blood traveling through organs, locating blood clots, locating aberration of the heart, and locating masses of the liver or kidney.

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